INSITE 2: A Fully Wireless Implantable, Multicolor Fluorescence Imager for Monitoring the Response to Cancer Therapy
Cellular-level in vivo imaging is critical in obtaining high-resolution, multicellular information in cancer therapy. One key application is monitoring the immune response in immunotherapy, a game-changing therapeutic that unleashes the immune system to attack cancer. While immunotherapy results in durable
responses for responders, detailed cellular-level information from multiple immune cell types is essential to assess the efficacy of the treatment and detect nonresponders. In this project, we propose a proof-of-concept “wireless microscope-on-chip”, leveraging innovations in optics and CMOS technology to detect small cell foci in real time and transmit the data through an ultrasonic link.
Expected Graduation Date:
May, 2028
