Microneedle Ion-Selective Electrodes for Wearable Electrolyte Monitoring
Ion-selective electrodes are electrochemical sensors that monitor changes in ion concentrations under near-zero current conditions, which makes them ideal for sensitive, low-power monitoring. Our work, in collaboration with Sandia National Lab, focuses on ion-selective electrodes for continuous, wearable
electrolyte monitoring. These ion-selective electrodes will be integrated into a microneedle patch to monitor electrolytes in interstitial fluid. To enable safe, calibration-free monitoring, our current work focuses on (1) transducer and ion-selective membrane compositions that improve the lifetime, stability,
and biocompatibility of K+, Na+, and Ca2+ sensors, and (2) material selection and deposition techniques that reduce the thickness of the transducer and ion-selective membrane layers allowing for microneedle integration.
